• Express System: E.coli
  • Product Tag: C-His-Avi
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FLLPTGAEA peptide
Catalog #MHC-HE452TC
Regular price $1,050.00
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APC-Labeled Human HLA-A*02:01&B2M&CG1 (FLLPTGAEA) Tetramer Protein (MHC-HE452TC) Summary

Product Description

Recombinant APC-Labeled Human HLA-A*02:01&B2M&CG1 (FLLPTGAEA) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-A*02:01&B2M&CG1 (FLLPTGAEA) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FLLPTGAEA peptide.

Product Background

Cathepsin G (CG) is a myeloid azurophil granule protease that is highly expressed by acute myeloid leukemia (AML) blasts and leukemia stem cells. CG1 (FLLPTGAEA) is a human leukocyte antigen-A2-restricted nonameric peptide derived from CG that can act as an immunogenic target in AML.

Product Category

Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&CG1 (FLLPTGAEA) Specifications

Protein
HLA-A*02:01&B2M&CG1 (FLLPTGAEA)
Synonyms
CG1 (FLLPTGAEA)

MHC Form

Tetramer

Allele

HLA-A*02:01
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FLLPTGAEA peptide
Product Tag
C-His-Avi

Fluorophore

APC
Expression System
E.coli

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 0.2% BSA (pH 8.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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