APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein (MHC-HM493TC) Summary
Product Description |
Recombinant APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide. |
Product Background |
Kita-Kyushu lung cancer antigen-1 (KK-LC-1), encoded by CT83, includes epitope peptides recognized by cytotoxic T lymphocytes (CTLs). CTLs against KK-LC-1 predominantly accumulate among tumor-infiltrating lymphocytes, which leads to a good response to adaptive immunotherapy. Except for the testis, KK-LC-1 is not expressed in normal tissues. It is expressed in 33%, 82%, and 75% of non-small cell lung cancers, GC, and triple-negative breast cancers, respectively. |
HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Specifications
Protein |
HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) |
Synonyms |
KK-LC-1; CT83; CXorf61; KKLC1;;KK-LC1 |
MHC Form |
Tetramer |
Allele |
HLA-A*02:01 |
Accession |
A0A140T913(HLA-A*02:01)&P61769(B2M)&ILNNFPHSI |
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide |
Product Tag |
C-His-Avi |
Fluorophore |
APC-Labeled |
Expression System |
HEK293 |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 100mM L-arginine, 0.2% BSA (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...