• Express System: HEK293
  • Product Tag: C-His-Avi
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide
Catalog #MHC-HM493TC
Regular price $1,050.00
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APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein (MHC-HM493TC) Summary

Product Description

Recombinant APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide.

Product Background

Kita-Kyushu lung cancer antigen-1 (KK-LC-1), encoded by CT83, includes epitope peptides recognized by cytotoxic T lymphocytes (CTLs). CTLs against KK-LC-1 predominantly accumulate among tumor-infiltrating lymphocytes, which leads to a good response to adaptive immunotherapy. Except for the testis, KK-LC-1 is not expressed in normal tissues. It is expressed in 33%, 82%, and 75% of non-small cell lung cancers, GC, and triple-negative breast cancers, respectively.

Product Category

Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Specifications

Protein
HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI)
Synonyms
KK-LC-1; CT83; CXorf61; KKLC1;

MHC Form

Tetramer

Allele

HLA-A*02:01
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide
Product Tag
C-His-Avi

Fluorophore

APC-Labeled
Expression System
HEK293

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 100mM L-arginine, 0.2% BSA (pH 7.4).
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Other Available Proteins:
Finding available proteins...
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