Name: APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein (MHC-HE011TC)
Brand: KactusBio
SKU: MHC-HE011TC-100UG
Price: 1265.0 USD
Availability: InStock

APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein (MHC-HE011TC)

Immobilized Anti-HLA-A*02:01&B2M&P53 R175H Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer, His Tag with the EC50 of 21.1ng/ml determined by ELISA.

Express System: E.coli
Product Tag: C-His-Avi
Activity: Immobilized Anti-HLA-A*02:01&B2M&P53 R175H Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer, His Tag with the EC50 of 21.1ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and HMTEVVRHC peptide

Catalog #MHC-HE011TC

Size

100UG

500UG

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APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein (MHC-HE011TC) Summary

Product Description	Recombinant APC-Labeled Human HLA-A02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A02:01), Ile21-Met119(B2M) and HMTEVVRHC peptide.
Product Background	p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Specifications

Protein	HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC)
Synonyms	MHC; HLA-A; P53; TP53; Antigen NY-CO-13; BCC7; FLJ92943; LFS1; TRP53
MHC Form	Tetramer
Allele	HLA-A*02:01
Accession	A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRHC
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and HMTEVVRHC peptide
Activity	Immobilized Anti-HLA-A02:01&B2M&P53 R175H Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for APC-Labeled Human HLA-A02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer, His Tag with the EC50 of 21.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Fluorophore	APC
Expression System	E.coli
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl, 0.2% BSA (pH 8.0).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized Anti-HLA-A*02:01&B2M&P53 R175H Antibody, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for APC-Labeled Human HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer, His Tag with the EC50 of 21.1ng/ml determined by ELISA.