Name: APC-Labeled Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein (MHC-HM468TA)
Brand: KactusBio
SKU: MHC-HM468TA-100UG
Price: 1265.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His-Avi
Amino Acid Range: Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide

Catalog #MHC-HM468TA

Size

100UG

500UG

Order by 4pm ET for delivery on:

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APC-Labeled Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein (MHC-HM468TA) Summary

Product Description	Recombinant APC-Labeled Human HLA-A03:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Specifications

Protein	HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK)
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Tetramer
Allele	HLA-A*03:01
Accession	NP_002107.3(HLA-A*03:01)&P61769(B2M)&VVVGADGVGK
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide
Product Tag	C-His-Avi
Fluorophore	APC
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300mM NaCl (pH 7.4).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.