Name: APC-Labeled Human HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM469TA)
Brand: KactusBio
SKU: MHC-HM469TA-100UG
Price: 1265.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His-Avi
Amino Acid Range: Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide

Catalog #MHC-HM469TA

Size

100UG

500UG

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Product Description	Recombinant APC-Labeled Human HLA-B07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-B07:02&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-B*07:02&B2M&KRAS G12D (GADGVGKSAL)
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Tetramer
Allele	HLA-B*07:02
Accession	P01889(HLA-B*07:02)&P61769(B2M)&GADGVGKSAL
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Val309(HLA-B*07:02), Ile21-Met119(B2M) and GADGVGKSAL peptide
Product Tag	C-His-Avi
Fluorophore	APC
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM PB, 450mM NaCl (pH 7.4).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.