Name: APC-Labeled Human HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein (MHC-HM492TC)
Brand: KactusBio
SKU: MHC-HM492TC-100UG
Price: 1265.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His-Avi
Amino Acid Range: Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide

Catalog #MHC-HM492TC

Size

100UG

500UG

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Product Description	Recombinant APC-Labeled Human HLA-C08:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. APC-Labeled Human HLA-C08:01&B2M&KRAS G12D (GADGVGKSAL) Tetramer is assembled by biotinylated monomer and APC-Labeled streptavidin.It contains Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-C*08:01&B2M&KRAS G12D (GADGVGKSAL)
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Tetramer
Allele	HLA-C*08:01
Accession	AAA59688.1(HLA-C*08:01)&P61769(B2M)&GADGVGKSAL
Species	Human
Biotinylated	no
Amino Acid Range	Cys25-Ala366(HLA-C*08:01), Ile21-Met119(B2M) and GADGVGKSAL peptide
Product Tag	C-His-Avi
Fluorophore	APC
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-Arginine (pH 7.4).
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.