• Express System: HEK293
  • Product Tag: C-mFc-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Canine PD-L1, mFc Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Canine PD-1, hFc Tag (Cat. PD1-DM201) with the EC50 of 0.26ug/ml determined by ELISA.
  • Amino Acid Range: Phe19-Arg236
Catalog #PDL-CM610B
Price
Regular price $578.00
Regular price Sale price $578.00
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Canine PD-L1/B7-H1 Protein (PDL-CM610B) Summary

Product Description

 Recombinant Biotinylated Canine PD-L1/B7-H1 Protein is expressed from HEK293 with mFc tag and Avi tag at the C-terminus.It contains Phe19-Arg236.

Product Background

 B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.

Product Category

 Recombinant Protein / Antibody discovery / Immune checkpoint proteins, ADC targets

Biotinylated Canine PD-L1/B7-H1 Protein (PDL-CM610B) Specifications/Details

Protein
 PD-L1/B7-H1
Synonyms
 CD274; PDL1; PD-L1; PD-L1B7 homolog 1;B7-H; B7H1; B7-H1; PDCD1L1; PDCD1LG1
Accession
Species
 Canine
Biotinylated
 yes
Amino Acid Range
 Phe19-Arg236
Molecular Weight
 The protein has a predicted MW of 52.91 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Biotinylated Canine PD-L1, mFc Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Canine PD-1, hFc Tag (Cat. PD1-DM201) with the EC50 of 0.26ug/ml determined by ELISA.
Product Tag
 C-mFc-Avi

Fluorophore

 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Canine PD-L1, mFc Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Canine PD-1, hFc Tag (Cat. PD1-DM201) with the EC50 of 0.26ug/ml determined by ELISA. Immobilized Biotinylated Canine PD-L1, mFc Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Canine PD-1, hFc Tag (Cat. PD1-DM201) with the EC50 of 0.26ug/ml determined by ELISA.
Biotinylated Canine PD-L1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Canine PD-L1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Canine PD-L1 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Canine PD-L1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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