- Express System: HEK293
- Product Tag: C-His-Avi
- Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
- Activity: Immobilized Biotinylated Cynomolgus ANGPTL3, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA.
- Amino Acid Range: Ser17-Glu460
Biotinylated Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein (ANG-CM403B) Summary
Product Description |
Recombinant Biotinylated Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Ser17-Glu460. |
Product Background |
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. |
Biotinylated Cynomolgus ANGPTL3/Angiopoietin-like 3 Protein (ANG-CM403B) Specifications/Details
Protein |
ANGPTL3/Angiopoietin-like 3 |
Synonyms |
ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3;ANG5;Angiopoietin 5; ANGPT-5; ANGPT 5 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
yes |
Amino Acid Range |
Ser17-Glu460 |
Molecular Weight |
The protein has a predicted MW of 55.19 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Cynomolgus ANGPTL3, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA. |
Product Tag |
C-His-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 0.05% CHAPS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
Other Available Proteins: