Name: Biotinylated Cynomolgus CD8 alpha Protein (CD8-CM4A8B)
Brand: KactusBio
SKU: CD8-CM4A8B-100UG
Price: 578.0 USD
Availability: InStock

Biotinylated Cynomolgus CD8 alpha Protein (CD8-CM4A8B)

Immobilized Biotinylated Cynomolgus CD8 alpha, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.

Biotinylated Cynomolgus CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Cynomolgus CD8 alpha, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
Amino Acid Range: Ser22-Asp182
Other Available Proteins:

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Catalog #CD8-CM4A8B

Size

100UG

500UG

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Biotinylated Cynomolgus CD8 alpha Protein (CD8-CM4A8B) Summary

Product Description	Recombinant Biotinylated Cynomolgus CD8 alpha Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Ser22-Asp182.
Product Background	CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Biotinylated Cynomolgus CD8 alpha Protein (CD8-CM4A8B) Specifications/Details

Protein	CD8 alpha/CD8A
Synonyms	CD8a; Lyt-2; CD8; Leu2; MAL; p32; CD8a molecule; OKT8 T-cell antigen
Accession	XP_065382910.1
Species	Cynomolgus
Biotinylated	yes
Amino Acid Range	Ser22-Asp182
Molecular Weight	The protein has a predicted MW of 20.6 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Cynomolgus CD8 alpha, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Biotinylated Cynomolgus CD8 alpha, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD8 Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
	Biotinylated Cynomolgus CD8 alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.