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Biotinylated Cynomolgus CD98 Protein (CD9-CM498B) Summary
Product Description |
Recombinant Biotinylated Cynomolgus CD98 Protein is expressed from HEK293 with His tag tag and Avi tag at the N-terminus.It contains Arg175-Ala599. |
Product Background |
The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Biotinylated Cynomolgus CD98 Protein (CD9-CM498B) Specifications/Details
Protein |
CD98 |
Synonyms |
4F2hc; CD98; SLC3A2; 4F2; CD98HC; MDU1; NACAE; 4T2HC |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
yes |
Amino Acid Range |
Arg175-Ala599 |
Molecular Weight |
The protein has a predicted MW of 49.83 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Cynomolgus CD98, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 1.8ng/ml determined by ELISA. |
Product Tag |
N-His-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 0.3M Arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Biotinylated Cynomolgus CD98, His Avi Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD98 Antibody, hFc Tag with the EC50 of 1.8ng/ml determined by ELISA. |
|
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Biotinylated Cynomolgus CD98 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Biotinylated Cynomolgus CD98 is greater than 90% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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