• Express System: HEK293
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Cynomolgus FcRH5 Domain, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 14.0ng/ml determined by ELISA.
  • Amino Acid Range: Val745-Thr850
Catalog #FCR-CM10DB
Price
Regular price $578.00
Regular price Sale price $578.00
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Cynomolgus FcRH5/FcRL5 Domain Protein (Primary Amine Labeling) (FCR-CM10DB) Summary

Product Description

 Recombinant Biotinylated Cynomolgus FcRH5/FcRL5 Domain Protein is expressed from HEK293 with His tag at the N-terminus.It contains Val745-Thr850.

Product Background

 FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.

Product Category

 Recombinant Protein / Antibody discovery / ADC targets

Biotinylated Cynomolgus FcRH5/FcRL5 Domain Protein (Primary Amine Labeling) (FCR-CM10DB) Specifications/Details

Protein
 FcRH5/FcRL5
Synonyms
 FcR-like protein 5; FcRH5; FcRL5; BXMAS1; CD307; CD307e; IFGP5; IRTA2
Accession
Species
 Cynomolgus
Biotinylated
 yes
Amino Acid Range
 Val745-Thr850
Molecular Weight
 The protein has a predicted MW of 12.3 kDa. Due to glycosylation, the protein migrates to 27-35 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Biotinylated Cynomolgus FcRH5 Domain, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 14.0ng/ml determined by ELISA.
Product Tag
 N-His

Fluorophore

 Biotin-labeled
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Cynomolgus FcRH5 Domain, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 14.0ng/ml determined by ELISA. Immobilized Biotinylated Cynomolgus FcRH5 Domain, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 14.0ng/ml determined by ELISA.
Biotinylated Cynomolgus FcRH5 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Cynomolgus FcRH5 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Cynomolgus FcRH5 Domain is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Cynomolgus FcRH5 Domain is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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