Name: Biotinylated Cynomolgus IFN alpha/beta R2 Protein (IFN-CM4R2B)
Brand: KactusBio
SKU: IFN-CM4R2B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Cynomolgus IFN alpha/beta R2 Protein (IFN-CM4R2B)

Biotinylated Cynomolgus IFN alpha/beta R2, His-Avi Tag captured on CM5 Chip via Anti-His Antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 0.13 uM as determined in SPR assay (Biacore T200).

Biotinylated Cynomolgus IFN alpha/beta R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Cynomolgus IFN alpha/beta R2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.13 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Ile27-Lys243

Catalog #IFN-CM4R2B

Size

100UG

500UG

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Biotinylated Cynomolgus IFN alpha/beta R2 Protein (IFN-CM4R2B) Summary

Product Description	Recombinant Biotinylated Cynomolgus IFN alpha/beta R2 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Ile27-Lys243.
Product Background	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Cynomolgus IFN alpha/beta R2 Protein (IFN-CM4R2B) Specifications/Details

Protein	IFN alpha/beta R2
Synonyms	IFN-R-2; IFNAR2; IFNARB; IFNABR; IFN-alpha; IFN-alpha/beta R2; IFNbR2; IFN-R; β receptor 2; β receptor10;
Accession	EHH53981.1
Species	Cynomolgus
Biotinylated	yes
Amino Acid Range	Ile27-Lys243
Molecular Weight	The protein has a predicted MW of 27.75 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.13 uM as determined in SPR assay (Biacore T200).
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Cynomolgus IFN alpha/beta R2, His-Avi Tag captured on CM5 Chip via Anti-His Antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 0.13 uM as determined in SPR assay (Biacore T200).
	Biotinylated Cynomolgus IFN alpha/beta R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Cynomolgus IFN alpha/beta R2 is greater than 95% as determined by SEC-HPLC.