Regular price
$578.00
Order by 4pm ET for delivery on:
Biotinylated Cynomolgus IL-18 Protein (IL1-CE618B) Summary
Product Description |
Recombinant Biotinylated Cynomolgus IL-18 Protein is expressed from E.coli with Avi tag at the C-terminus.It contains Tyr37-Asp193. |
Product Background |
Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Biotinylated Cynomolgus IL-18 Protein (IL1-CE618B) Specifications/Details
Protein |
IL-18 |
Synonyms |
IL-18; IL18; IGIF; IL-1F4; IL-1 gamma; IL1F4; IL-1g; Interleukin 1 |
Accession |
|
Species |
Cynomolgus |
Biotinylated |
yes |
Amino Acid Range |
Tyr37-Asp193 |
Molecular Weight |
The protein has a predicted MW of 20.34 kDa same as Bis-Tris PAGE result. |
Activity |
Immobilized Cynomolgus IL-18BP, His Tag (Cat. IL8-CM1BP) at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Cynomolgus IL-18, Avi Tag with the EC50 of 3.2ng/ml determined by ELISA. |
Product Tag |
C-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Immobilized Cynomolgus IL-18BP, His Tag (Cat. IL8-CM1BP) at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Cynomolgus IL-18, Avi Tag with the EC50 of 3.2ng/ml determined by ELISA. |
|
|
Biotinylated Cynomolgus IL-18 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
Loaded Biotinylated Cynomolgus IL-18, Avi Tag on Steptavidin-Biosensor can bind Cynomolgus IL-18 R1, His Tag (Cat. IL8-CM1R1) with an affinity constant of 4.11 nM as determined in BLI assay. |
|
|
The purity of Biotinylated Cynomolgus IL-18 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
