Biotinylated Cynomolgus IL-2 R beta/CD122 Protein (CD1-CM422B)

Biotinylated Cynomolgus IL-2 R beta, His-Avi Tag captured on CM5 Chip via SA can bind Human IL-2, No Tag (Cat. IL2-HM001) with an affinity constant of 0.16 uM as determined in SPR assay (Biacore T200).

Biotinylated Cynomolgus IL-2 R beta, His-Avi Tag captured on CM5 Chip via SA can bind Human IL-15, No Tag (Cat. IL5-HE015) with an affinity constant of 11.63 nM as determined in SPR assay (Biacore T200).

Biotinylated Cynomolgus IL-2 R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Cynomolgus IL-2 R beta is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 0.16 uM as determined in SPR assay (Biacore T200).
Amino Acid Range: Ala27-Thr240

Catalog #CD1-CM422B

Price

$578⁰⁰

Size

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Biotinylated Cynomolgus IL-2 R beta/CD122 Protein (CD1-CM422B) Summary

Product Description

Recombinant Biotinylated Cynomolgus IL-2 R beta/CD122 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Ala27-Thr240.

Product Background

IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. Functional IL-2 receptors can exist in two affinity states on cell surfaces, the high affinity complex consisting of heterotrimers of the alpha, beta, and gamma chains, and the intermediate affinity complex comprising heterodimers of the beta and gamma chains.

Biotinylated Cynomolgus IL-2 R beta/CD122 Protein (CD1-CM422B) Specifications/Details

Protein	IL-2 R beta/CD122
Synonyms	CD122; IL-15 R beta; IL-2 R beta; IL-2R subunit beta; IL2RB; P70-75; p75; RP5-1170K4.6; IL-15 R β; IL-2 R β; IL-2R subunit β;IL15R beta; IL2R beta; IL2R subunit beta; IL15R β; IL2R β; IL2R subunit β;IL-15 R b; IL15R b; IL-2 R b; IL2R b; IL-2R subunit b; IL2R subunit b
Accession	Q38J85
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ala27-Thr240
Molecular Weight	The protein has a predicted MW of 27.69 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 0.16 uM as determined in SPR assay (Biacore T200).
Product Tag	C-His-Avi
Fluorophore	Biotin-labeled
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Cynomolgus IL-2 R beta, His-Avi Tag captured on CM5 Chip via SA can bind Human IL-2, No Tag (Cat. IL2-HM001) with an affinity constant of 0.16 uM as determined in SPR assay (Biacore T200).
	Biotinylated Cynomolgus IL-2 R beta, His-Avi Tag captured on CM5 Chip via SA can bind Human IL-15, No Tag (Cat. IL5-HE015) with an affinity constant of 11.63 nM as determined in SPR assay (Biacore T200).
	Biotinylated Cynomolgus IL-2 R beta on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Cynomolgus IL-2 R beta is greater than 95% as determined by SEC-HPLC.