Biotinylated Cynomolgus LY6G6D Protein (LYD-CM46DB)
  • Express System: HEK293
  • Product Tag: N-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Cynomolgus LY6G6D, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA.
  • Amino Acid Range: Asn20-Ser104
Catalog #LYD-CM46DB
Regular price $578.00
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Biotinylated Cynomolgus LY6G6D Protein (LYD-CM46DB) Summary

Product Description

Recombinant Biotinylated Cynomolgus LY6G6D Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Asn20-Ser104.

Product Background

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Biotinylated Cynomolgus LY6G6D Protein (LYD-CM46DB) Specifications/Details

Protein
LY6G6D
Synonyms
Protein Ly6-D; C6orf23; G6D; MEGT1; NG25
Accession
Species
Cynomolgus
Biotinylated
yes
Amino Acid Range
Asn20-Ser104
Molecular Weight
The protein has a predicted MW of 12.03 kDa. Due to glycosylation, the protein migrates to 18-25 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Biotinylated Cynomolgus LY6G6D, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA.
Product Tag
N-His-Avi
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Cynomolgus LY6G6D, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA. Immobilized Biotinylated Cynomolgus LY6G6D, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-LY6G6D Antibody, hFc Tag with the EC50 of 5.0ng/ml determined by ELISA.
Biotinylated Cynomolgus LY6G6D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Cynomolgus LY6G6D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Cynomolgus LY6G6D is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Cynomolgus LY6G6D is greater than 95% as determined by SEC-HPLC.
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