Biotinylated Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein (Primary Amine Labeling) (TRL-CM1R2B)

Immobilized Biotinylated Cynomolgus TRAIL R2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TRAIL R2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).

Biotinylated Cynomolgus TRAIL R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Cynomolgus TRAIL R2 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Activity: Immobilized Biotinylated Cynomolgus TRAIL R2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TRAIL R2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Ile58-Ser212

Catalog #TRL-CM1R2B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.It contains Ile58-Ser212.
Product Background	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Product Category	Recombinant Protein / Antibody discovery

Protein	TRAIL R2/DR5/TNFRSF10B
Synonyms	CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER
Accession	A0A2K5TXK0
Species	Cynomolgus
Biotinylated	yes
Amino Acid Range	Ile58-Ser212
Molecular Weight	The protein has a predicted MW of 18.28 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Cynomolgus TRAIL R2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TRAIL R2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Cynomolgus TRAIL R2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-TRAIL R2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA (QC Test).
	Biotinylated Cynomolgus TRAIL R2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Cynomolgus TRAIL R2 is greater than 95% as determined by SEC-HPLC.