Name: Biotinylated Human 2B4/CD244/SLAMF4 Protein (2B4-HM401B)
Brand: KactusBio
SKU: 2B4-HM401B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human 2B4/CD244/SLAMF4 Protein (2B4-HM401B)

Immobilized Biotinylated Human 2B4, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human CD48, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA (QC Test).

Biotinylated Human 2B4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human 2B4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human 2B4, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human CD48, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Cys22-Arg221

Catalog #2B4-HM401B

Size

100UG

500UG

Order now, ships by:

[{"id":42605872873694,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"2B4-HM401B-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human 2B4\/CD244\/SLAMF4 Protein (2B4-HM401B) - 100UG","public_title":"100UG","options":["100UG"],"price":57750,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584221544670,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"2B4-HM401B-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human 2B4\/CD244\/SLAMF4 Protein (2B4-HM401B) - 500UG","public_title":"500UG","options":["500UG"],"price":192500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Biotinylated Human 2B4/CD244/SLAMF4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Cys22-Arg221.
Product Background	2B4 (CD244) is expressed by memory-phenotype CD8(+) T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	2B4/CD244/SLAMF4
Synonyms	2B4; CD244 antigen; CD244; h2B4; NAIL; NKR2B4; Nmrk; SLAMF4
Accession	Q9BZW8-2
Species	Human
Biotinylated	yes
Amino Acid Range	Cys22-Arg221
Molecular Weight	The protein has a predicted MW of 24.9 kDa. Due to glycosylation, the protein migrates to 48-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human 2B4, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human CD48, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human 2B4, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human CD48, hFc Tag with the EC50 of 2.9ng/ml determined by ELISA (QC Test).
	Biotinylated Human 2B4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human 2B4 is greater than 95% as determined by SEC-HPLC.

Product Description

Product Background

Product Category

Product Tag