Biotinylated Human 4-1BB/TNFRSF9 Protein (BB4-HM441B)
Catalog: BB4-HM441B
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| Product Description | Recombinant Biotinylated Human 4-1BB/TNFRSF9 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu24-Gln186. |
Product Background |
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. |
Product Category |
Recombinant Protein |
Target |
4-1BB/TNFRSF9 |
| Synonyms | CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA |
Gene/Protein ID |
Q07011 |
Species |
Human |
Exact Sequence |
Leu24-Gln186 |
| Molecular Weight | The protein has a predicted MW of 20.2 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human 4-1BB Ligand (Trimer), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human 4-1BB, His Tag with the EC50 of 0.16ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Immobilized Human 4-1BB Ligand (Trimer), His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human 4-1BB, His Tag with the EC50 of 0.16ug/ml determined by ELISA. |
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The purity of Biotinylated Human 4-1BB is greater than 95% as determined by SEC-HPLC. |
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Biotinylated Human 4-1BB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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