Name: Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein (MHC-HM432B)
Brand: KactusBio
SKU: MHC-HM432B-100UG
Price: 341.0 USD
Availability: InStock

Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein (MHC-HM432B)

Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide

Catalog #MHC-HM432B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human HLA-A02:03&B2M&AFP (FMNKFIYEI) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus..It contains Gly25-Thr305(HLA-A02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide.
Product Background	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-A*02:03&B2M&AFP (FMNKFIYEI)
Synonyms	Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA; MHC
MHC Form	Monomer
Allele	HLA-A*02:03
Accession	AAA03604.1(HLA-A*02:03)&P61769(B2M)&FMNKFIYEI
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Thr305(HLA-A*02:03), Ile21-Met119(B2M) and FMNKFIYEI peptide
Molecular Weight	The protein has a predicted MW of 50.70 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer is greater than 95% as determined by SEC-HPLC.