Product Description |
Recombinant Biotinylated Human APOE3/Apolipoprotein E Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Lys19-His317. |
Product Background |
Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). |
Product Category |
Recombinant Protein |
Target |
APOE3/Apolipoprotein E |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Lys19-His317 |
Molecular Weight |
The protein has a predicted MW of 37.66 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Biotinylated Human APOE3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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