Name: Biotinylated Human BDCA-2 Protein (BCA-HM402B)
Brand: KactusBio
SKU: BCA-HM402B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human BDCA-2 Protein (BCA-HM402B)

Immobilized Biotinylated Human BDCA-2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.

Biotinylated Human BDCA-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: N-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Human BDCA-2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe46-Ile213

Catalog #BCA-HM402B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human BDCA-2 Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Phe46-Ile213.
Product Background	BDCA-2 is a novel type II C-type lectin specifically expressed by plasmacytoid dendritic cells (PDCs) that can internalize antigen for presentation to T cells. Furthermore, signaling via BDCA-2 may play a role in switching from interferon (IFN)-α/β-controlled to interleukin (IL)-12-controlled immune response pathways, as triggering of BDCA-2 potently inhibits secretion of IFN-α/β by PDCs and thereby promotes IL-12 p70 production in PDCs and other cells.
Product Category	Recombinant Protein / Antibody discovery

Protein	BDCA-2
Synonyms	BDCA-2; BDCA2; CLECSF11; CLECSF7; DLEC; HECL; CLEC4C; CD303;
Accession	Q8WTT0-1
Species	Human
Biotinylated	yes
Amino Acid Range	Phe46-Ile213
Molecular Weight	The protein has a predicted MW of 22.7 kDa. Due to glycosylation, the protein migrates to 33-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human BDCA-2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 300mM NaCl, 300mM L-arginine (pH 8.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human BDCA-2, His Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-BDCA-2 Antibody, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.
	Biotinylated Human BDCA-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.