Biotinylated Human CCR2b Protein-VLP (CCR-HM02BB)
Catalog: CCR-HM02BB
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| Product Description | Recombinant Biotinylated Human CCR2b Protein-VLP is expressed from HEK293.It contains Met1-Leu360. |
Product Background |
The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures. |
Product Category |
Recombinant Protein |
Target |
CCR2b |
| Synonyms | C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2 |
Gene/Protein ID |
P41597-2 |
Species |
Human |
Exact Sequence |
Met1-Leu360 |
| Molecular Weight | The target protein has a predicted MW of 42.9kDa. |
Activity |
The affinity constant of 5.24 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Express System |
HEK293 |
| Purity | > 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Biotinylated Human CCR2b VLP captured on SA Chip can bind Anti-CCR2b Antibody with an affinity constant of 5.24 nM as determined in SPR assay (Biacore T200). |
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The purity of Biotinylated Human CCR2b VLP is greater than 95% as determined by SEC-HPLC. |
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