Name: Biotinylated Human CCR2b Protein-VLP (CCR-HM02BB)
Brand: KactusBio
SKU: CCR-HM02BB-100UG
Price: 1969.0 USD
Availability: InStock

Biotinylated Human CCR2b Protein-VLP (CCR-HM02BB)

Biotinylated CCR2B VLP captured on CM5 Chip via streptavidin can bind Anti-CCR2 Antibody, hFc with an affinity constant of 2.19 nM as determined in SPR assay (Biacore T200) (QC Test).

Immobilized Biotinylated Human CCR2b VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR2 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test).

The purity of Biotinylated Human CCR2b VLP is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Biotinylated Human CCR2b VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR2 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 2.19 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Leu360

Catalog #CCR-HM02BB

Size

100UG

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Product Description	Recombinant Biotinylated Human CCR2b Protein-VLP is expressed from HEK293.It contains Met1-Leu360.
Product Background	The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein	CCR2b
Synonyms	C-C CKR-2; CCR-2; CCR2; MCP-1-R; CMKBR2; CCR2
Accession	P41597-2
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Leu360
Molecular Weight	The target protein has a predicted MW of 42.9kDa.
Activity	Immobilized Biotinylated Human CCR2b VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR2 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test). The affinity constant of 2.19 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated CCR2B VLP captured on CM5 Chip via streptavidin can bind Anti-CCR2 Antibody, hFc with an affinity constant of 2.19 nM as determined in SPR assay (Biacore T200) (QC Test).
	Immobilized Biotinylated Human CCR2b VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR2 Antibody, hFc Tag with the EC50 of 0.21ug/ml determined by ELISA (QC Test).
	The purity of Biotinylated Human CCR2b VLP is greater than 95% as determined by SEC-HPLC.