• Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human CCR4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA. The affinity constant of 0.64 nM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Met1-Leu360
Catalog #CCR-HM14NB
Price
Regular price $2,16600
Regular price Sale price $2,16600
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human CCR4 Nanodisc (CCR-HM14NB) Summary

Product Description

 Recombinant Biotinylated Human CCR4 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Leu360.

Product Background

 CC chemokine receptor 4 (CCR4) is a chemokine receptor mainly expressed by T cells. CCR4 is important in the pathogenesis of many diseases, such as diabetes, multiple sclerosis, asthma, dermatitis, and cancer. This review briefly characterizes CCR4 and its ligands (CCL17, CCL22, and CCL2), and their contributions to immunological and neoplastic diseases.

Biotinylated Human CCR4 Nanodisc (CCR-HM14NB) Specifications/Details

Protein
 CCR4
Synonyms
 C-C CKR-4; CC-CKR-4; CCR-4; CCR4; K5-5; CD194; CMKBR4; CKR-4;C-C CKR4; CC-CKR4; CKR4
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Met1-Leu360
Molecular Weight
 The protein has a predicted MW of 54.3 kDa.
Activity
 Immobilized Biotinylated Human CCR4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA. The affinity constant of 0.64 nM as determined in SPR assay (Biacore T200).
Product Tag
 C-His
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
 Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human CCR4 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CCR4 Antibody, hFc Tag with an affinity constant of 0.64 nM as determined in SPR assay (Biacore T200). Biotinylated Human CCR4 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CCR4 Antibody, hFc Tag with an affinity constant of 0.64 nM as determined in SPR assay (Biacore T200).
Immobilized Biotinylated Human CCR4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA. Immobilized Biotinylated Human CCR4 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR4 Antibody, hFc Tag with the EC50 of 7.5ng/ml determined by ELISA.
Other Available Proteins:
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