Name: Biotinylated Human CCR7 Nanodisc (CCR-HM17NB)
Brand: KactusBio
SKU: CCR-HM17NB-100UG
Price: 2165.9 USD
Availability: InStock

Biotinylated Human CCR7 Nanodisc (CCR-HM17NB)

Biotinylated Human CCR7 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 2.99 nM as determined in SPR assay (Biacore T200).

Immobilized Biotinylated Human CCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA (QC Test).

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human CCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA (QC Test). The affinity constant of 2.99 nM as determined in SPR assay (Biacore T200).
Recomended Products: Biotinylated Nanodisc Control (CON-HM1NB)
Amino Acid Range: Met1-Pro378

Catalog #CCR-HM17NB

Size

100UG

Order by 4pm ET for delivery on:

Biotinylated Human CCR7 Nanodisc (CCR-HM17NB) Summary

Product Description	Recombinant Biotinylated Human CCR7 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro378.
Product Background	CC-chemokine receptor 7 (CCR7), collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a series of inflammatory diseases due to the chaotic dendritic cell trafficking.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human CCR7 Nanodisc (CCR-HM17NB) Specifications/Details

Protein	CCR7
Synonyms	CCR7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; EBI1; CD197; CMKBR7; EBI1; EVI1
Accession	P32248
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Pro378
Molecular Weight	The protein has a predicted MW of 55.80 kDa.
Activity	Immobilized Biotinylated Human CCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA (QC Test). The affinity constant of 2.99 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human CCR7 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CCR7 Antibody, hFc Tag with an affinity constant of 2.99 nM as determined in SPR assay (Biacore T200).
	Immobilized Biotinylated Human CCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR7 Antibody, hFc Tag with the EC50 of 23.7ng/ml determined by ELISA (QC Test).