Biotinylated Human CD20 Protein-Nanodisc (CD2-HM12NB)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml(100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rituximab, hFc Tag with the EC50 of 0.70ug/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Met1-Pro297
Catalog #CD2-HM12NB
Regular price $2,165.90
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Product Description

Recombinant Biotinylated Human CD20 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Pro297.

Product Background

B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

CD20

Synonyms

MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Met1-Pro297

Molecular Weight

The protein has a predicted MW of 46.0 kDa.

Activity

Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml(100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rituximab, hFc Tag with the EC50 of 0.70ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml(100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rituximab, hFc Tag with the EC50 of 0.70ug/ml determined by ELISA. Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml(100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Rituximab, hFc Tag with the EC50 of 0.70ug/ml determined by ELISA.
Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Obinutuzumab, hFc Tag with the EC50 of 0.09ug/ml determined by ELISA. Immobilized Biotinylated Human CD20 Nanodisc, His Tag at 10ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Obinutuzumab, hFc Tag with the EC50 of 0.09ug/ml determined by ELISA.
Immobilized Ofatumumab, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human CD20 Nanodisc, His Tag with the EC50 of 2.57ug/ml determined by ELISA. Immobilized Ofatumumab, hFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Biotinylated Human CD20 Nanodisc, His Tag with the EC50 of 2.57ug/ml determined by ELISA.

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support@kactusbio.us

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