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Biotinylated Human CD44v9 Protein (CDX-HM4V9B) Summary
Product Description |
Recombinant Biotinylated Human CD44v9 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln21-Pro220 & Gly506-Ser534. |
Product Background |
CD44 is a hyaluronan binding cell surface signal transducing receptor that influences motility, cell survival and proliferation as well as the formation of tumor microenvironment. CD44 contains two variable regions encoded by variable exons. Alternative splicing, which is often deregulated in cancer, can produce various isoforms of CD44 with properties that may have different tissue specific effects and therefore even diverse effects on cancer progression |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Biotinylated Human CD44v9 Protein (CDX-HM4V9B) Specifications/Details
Protein |
CD44 |
Synonyms |
CD44; CDw44; Epican; ECMR-III; LHR; MDU2; MDU3; MIC4; PGP-I; CSPG8; HCELL; HUTCH-I; IN; MC56 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Gln21-Pro220 & Gly506-Ser534 |
Molecular Weight |
The protein has a predicted MW of 28.13 kDa. Due to glycosylation, the protein migrates to 45-65 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Human CD44v9, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD44v9 Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. |
Product Tag |
C-His-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Biotinylated Human CD44v9, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CD44v9 Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. |
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Biotinylated Human CD44v9 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Biotinylated Human CD44v9 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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