Biotinylated Human CDH17/Cadherin 17 Domain 5-7 Protein (Primary Amine Labeling) (CDH-HM1D4B)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Biotinylated: yes
  • Exact Sequence: Glu450-Gly777

Catalog: CDH-HM1D4B

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Product Description Recombinant Biotinylated Human CDH17/Cadherin 17 Domain 5-7 Protein(Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu450-Gly777.

Product Background

 Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Product Category

 Recombinant Protein

Target

 CDH17/Cadherin 17 Domain 5-7

Gene/Protein ID

 Q12864

Species

 Human

Exact Sequence

 Glu450-Gly777
Molecular Weight The protein has a predicted MW of 36.79 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

Product Tag

 C-His

Express System

 HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Human CDH17 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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