Biotinylated Human CEACAM-8/CD66b Protein (CAM-HM408B)
Biotinylated Human CEACAM-8/CD66b Protein (CAM-HM408B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 6.13 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln35-Ser319
Catalog #CAM-HM408B
Regular price $525.00
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Product Description

Recombinant Biotinylated Human CEACAM-8/CD66b Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln35-Ser319.

Product Background

Eosinophils and their products are likely important in the pathophysiology of allergic diseases, such as bronchial asthma, and in host immunity to parasitic organisms. CD66b (CEACAM8, CGM6, NCA-95) is a single chain, GPI-anchored, highly glycosylated protein belonging to the carcinoembryonic Ag supergene family. CD66b is an activation marker for human granulocytes.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets

Protein

CEACAM-8/CD66b

Synonyms

CD66b; CEACAM8; CGM6; CD67; NCA-95

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Gln35-Ser319

Molecular Weight

The protein has a predicted MW of 34.3 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Activity

The affinity constant of 6.13 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human CEACAM-8, His Tag immobilized on CM5 Chip can bind Human CEACAM-6, His Tag with an affinity constant of 6.13 uM as determined in SPR assay (Biacore T200). Biotinylated Human CEACAM-8, His Tag immobilized on CM5 Chip can bind Human CEACAM-6, His Tag with an affinity constant of 6.13 uM as determined in SPR assay (Biacore T200).
Biotinylated Human CEACAM-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human CEACAM-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human CEACAM-8 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human CEACAM-8 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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