Name: Biotinylated Human Claudin 18.2 Protein-Nanodisc (CLD-HM10NB)
Brand: KactusBio
SKU: CLD-HM10NB-100UG
Price: 2166.0 USD
Availability: InStock

Biotinylated Human Claudin 18.2 Protein-Nanodisc (CLD-HM10NB)

Biotinylated Human Claudin 18.2 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-Claudin18.2 Antibody with an affinity constant of 5.72 nM as determined in SPR assay (Biacore T200).

Immobilized Biotinylated Human Claudin 18.2 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin18.2 Antibody, hFc Tag with the EC50 of 52.2ng/ml determined by ELISA.

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human Claudin 18.2 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin18.2 Antibody, hFc Tag with the EC50 of 52.2ng/ml determined by ELISA. The affinity constant of 5.72 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Val261

Catalog #CLD-HM10NB

Size

100UG

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Product Description	Recombinant Biotinylated Human Claudin 18.2 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val261.
Product Background	Claudin18 (CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	Claudin 18.2
Synonyms	CLDN18; CLDN18.2; Claudin-18.2; Claudin18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Accession	P56856-2
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Val261
Molecular Weight	The protein has a predicted MW of 40.60 kDa.
Activity	Immobilized Biotinylated Human Claudin 18.2 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin18.2 Antibody, hFc Tag with the EC50 of 52.2ng/ml determined by ELISA. The affinity constant of 5.72 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-Arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Biotinylated Human Claudin 18.2 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-Claudin18.2 Antibody with an affinity constant of 5.72 nM as determined in SPR assay (Biacore T200).
	Immobilized Biotinylated Human Claudin 18.2 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin18.2 Antibody, hFc Tag with the EC50 of 52.2ng/ml determined by ELISA.