Product Description |
Recombinant Biotinylated Full length Human Claudin 18.2 Protein-VLP is expressed from HEK293.It contains Met1-Val261. |
Product Background |
Claudin18(CLDN18) belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants,CLDN18.1 and CLDN18.2. Isoform 2 (Claudin 18.2) is abundant in gastric tumors. |
Product Category |
Recombinant Protein |
Target |
Claudin 18.2 |
Synonyms |
CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Val261 |
Molecular Weight |
The target protein has a predicted MW of 29 kDa. |
Activity |
The affinity constant of 1.28 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Express System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ul by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Biotinylated Human Claudin18.2 VLP captured on CM5 Chip via Streptavidin can bind Anti-Claudin18.2 Antibody with an affinity constant of 1.28 nM as determined in SPR assay (Biacore T200) (QC Test). |
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The purity of Biotinylated Human Claudin 18.2 VLP is greater than 95% as determined by SEC-HPLC. |
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