• Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human Claudin 6 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
  • Negative Control: Biotinylated Nanodisc Control (CON-HM1NB)
  • Amino Acid Range: Met1-Val220
Catalog #CLD-HM16NB
Price
Regular price $2,16590
Regular price Sale price $2,16590
/
Size
Avantor VWR Fisher Scientific

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Biotinylated Human Claudin 6 Nanodisc (CLD-HM16NB) Summary

Product Description

 Recombinant Biotinylated Human Claudin 6 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val220.

Product Background

 Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.

Biotinylated Human Claudin 6 Nanodisc (CLD-HM16NB) Specifications/Details

Protein
 Claudin 6
Synonyms
 Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2
Accession
Species
 Human
Biotinylated
 yes
Amino Acid Range
 Met1-Val220
Molecular Weight
 The protein has a predicted MW of 36.20 kDa.
Activity
 Immobilized Biotinylated Human Claudin 6 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
Product Tag
 C-His
Fluorophore
 Biotin-labeled
Expression System
 HEK293
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
 Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Human Claudin 6 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human Claudin 6 Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 2.5ng/ml determined by ELISA (QC Test).
Loaded Biotinylated Human Claudin 6 Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-Claudin6 Antibody, mFc Tag with an affinity constant of 0.35 nM as determined in BLI assay . Loaded Biotinylated Human Claudin 6 Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-Claudin6 Antibody, mFc Tag with an affinity constant of 0.35 nM as determined in BLI assay .
Other Available Proteins:
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