Name: Biotinylated Human CLEC12A/MICL/CLL-1 Protein (CLE-HM42AB)
Brand: KactusBio
SKU: CLE-HM42AB-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human CLEC12A/MICL/CLL-1 Protein (CLE-HM42AB)

Immobilized Biotinylated Human CLEC12A, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA.

Biotinylated Human CLEC12A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human CLEC12A is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His,C-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human CLEC12A, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: His65-Ala265

Catalog #CLE-HM42AB

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus and Avi tag at the C-Terminus.It contains His65-Ala265.
Product Background	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	CLEC12A/MICL/CLL-1
Synonyms	MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
Accession	Q5QGZ9-2
Species	Human
Biotinylated	yes
Amino Acid Range	His65-Ala265
Molecular Weight	The protein has a predicted MW of 26.4 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human CLEC12A, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His,C-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human CLEC12A, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CLEC12A Antibody, hFc Tag with the EC50 of 29.6ng/ml determined by ELISA.
	Biotinylated Human CLEC12A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human CLEC12A is greater than 95% as determined by SEC-HPLC.