Name: Biotinylated Human CXCR7 Nanodisc (CXR-HM17NB)
Brand: KactusBio
SKU: CXR-HM17NB-100UG
Price: 2166.0 USD
Availability: InStock

Biotinylated Human CXCR7 Nanodisc (CXR-HM17NB)

Biotinylated Human CXCR7 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CXCR7 Antibody 1, hFc Tag with an affinity constant of 3.22 nM as determined in SPR assay (Biacore T200).

Immobilized Biotinylated Human CXCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR7 Antibody 1, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA.

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human CXCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR7 Antibody 1, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA. The affinity constant of 3.22 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Met1-Lys362

Catalog #CXR-HM17NB

Size

100UG

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Biotinylated Human CXCR7 Nanodisc (CXR-HM17NB) Summary

Product Description	Recombinant Biotinylated Human CXCR7 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Lys362.
Product Background	Atypical chemokine receptor 3 (ACKR3), previously known as C-X-C chemokine receptor type 7 (CXCR7), has emerged as a key player in several biologic processes, particularly during development. Its CXCL11 and CXCL12 scavenging activity and atypical signaling properties, together with a new array of other nonchemokine ligands, have established ACKR3 as a main regulator of physiologic processes at steady state and during inflammation.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human CXCR7 Nanodisc (CXR-HM17NB) Specifications/Details

Protein	CXCR7
Synonyms	CXC-R7; CXCR-7; ACKR3; CMKOR1; GPR159; RDC1; RDC-1
Accession	P25106
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Lys362
Molecular Weight	The protein has a predicted MW of 54.4 kDa.
Activity	Immobilized Biotinylated Human CXCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR7 Antibody 1, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA. The affinity constant of 3.22 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human CXCR7 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-CXCR7 Antibody 1, hFc Tag with an affinity constant of 3.22 nM as determined in SPR assay (Biacore T200).
	Immobilized Biotinylated Human CXCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR7 Antibody 1, hFc Tag with the EC50 of 24.2ng/ml determined by ELISA.
	Immobilized Biotinylated Human CXCR7 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR7 Antibody 2, hFc Tag with the EC50 of 3.5ng/ml determined by ELISA.