Biotinylated Human DDR1 Protein (DDR-HM4R1B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Human DDR1, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-DDR1 Antibody, hFc Tag with the EC50 of 7.0ng/ml determined by ELISA.
  • Amino Acid Range: Asp21-Ala417
Catalog #DDR-HM4R1B
Regular price $578.00
/
Size

Order by 4pm ET for delivery on:

Biotinylated Human DDR1 Protein (DDR-HM4R1B) Summary

Product Description

Recombinant Biotinylated Human DDR1 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Asp21-Ala417.

Product Background

Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1's biology is elusive, with unknown downstream activation pathways; however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Biotinylated Human DDR1 Protein (DDR-HM4R1B) Specifications/Details

Protein
DDR1
Synonyms
HGK2; MCK-10; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; CD167a; EC 2.7.10.1
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Asp21-Ala417
Molecular Weight
The protein has a predicted MW of 46.93 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Biotinylated Human DDR1, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-DDR1 Antibody, hFc Tag with the EC50 of 7.0ng/ml determined by ELISA.
Product Tag
C-His-Avi
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Biotinylated Human DDR1, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-DDR1 Antibody, hFc Tag with the EC50 of 7.0ng/ml determined by ELISA. Immobilized Biotinylated Human DDR1, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-DDR1 Antibody, hFc Tag with the EC50 of 7.0ng/ml determined by ELISA.
Biotinylated Human DDR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human DDR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human DDR1 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human DDR1 is greater than 95% as determined by SEC-HPLC.
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Recently viewed