Name: Biotinylated Human FcRH5/FcRL5 Domain Protein (FCR-HM40DB)
Brand: KactusBio
SKU: FCR-HM40DB-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human FcRH5/FcRL5 Domain Protein (FCR-HM40DB)

Immobilized Biotinylated Human FcRH5 Domain, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.

Biotinylated Human FcRH5 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Anti-FcRH5 Antibody, hFc Tag on ProA-Biosensor can bind Biotinylated Human FcRH5 Domain, His-Avi Tag with an affinity constant of 1.10 nM as determined in BLI assay (Gator® Prime).

The purity of Biotinylated Human FcRH5 Domain is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human FcRH5 Domain, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.
Amino Acid Range: Val745-Thr850

Catalog #FCR-HM40DB

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human FcRH5/FcRL5 Domain Protein (FCR-HM40DB) Summary

Product Description	Recombinant Biotinylated Human FcRH5/FcRL5 Domain Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Val745-Thr850.
Product Background	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Biotinylated Human FcRH5/FcRL5 Domain Protein (FCR-HM40DB) Specifications/Details

Protein	FcRH5/FcRL5
Synonyms	FcR-like protein 5; FcRH5; FcRL5; BXMAS1; CD307; CD307e; IFGP5; IRTA2
Accession	Q96RD9-1
Species	Human
Biotinylated	yes
Amino Acid Range	Val745-Thr850
Molecular Weight	The protein has a predicted MW of 14.0 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human FcRH5 Domain, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.
Product Tag	N-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Biotinylated Human FcRH5 Domain, His-Avi Tag at 0.5ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA.
	Biotinylated Human FcRH5 Domain on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-FcRH5 Antibody, hFc Tag on ProA-Biosensor can bind Biotinylated Human FcRH5 Domain, His-Avi Tag with an affinity constant of 1.10 nM as determined in BLI assay (Gator® Prime).
	The purity of Biotinylated Human FcRH5 Domain is greater than 95% as determined by SEC-HPLC.