Biotinylated Human FGFR3 beta (IIIb) Protein (FGF-HM4BBB)
Biotinylated Human FGFR3 beta (IIIb) Protein (FGF-HM4BBB)
Biotinylated Human FGFR3 beta (IIIb) Protein (FGF-HM4BBB)
Biotinylated Human FGFR3 beta (IIIb) Protein (FGF-HM4BBB)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Biotinylated Human FGFR3 beta (IIIb) , His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Asp127-Gly377
Catalog #FGF-HM4BBB
Regular price $577.50
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Product Description

Recombinant Biotinylated Human FGFR3 beta (IIIb) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp127-Gly377.

Product Background

Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

FGFR3 bata (IIIb)

Synonyms

ACH; CD333; CEK; CEK2; EC 2.7.10; FGF R3; FGFR3; HSFGFR3EX; JTK4

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Asp127-Gly377

Molecular Weight

The protein has a predicted MW of 30.5 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Biotinylated Human FGFR3 beta (IIIb) , His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human FGFR3 beta (IIIb) , His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. Immobilized Biotinylated Human FGFR3 beta (IIIb) , His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA.
Biotinylated Human FGFR3 beta (IIIb) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human FGFR3 beta (IIIb) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human FGFR3 beta (IIIb) is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human FGFR3 beta (IIIb) is greater than 95% as determined by SEC-HPLC.

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