Biotinylated Human FGFR4 Protein (FGF-HM4R4B)
Biotinylated Human FGFR4 Protein (FGF-HM4R4B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu22-Asp369
Catalog #FGF-HM4R4B
Regular price $577.50
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Product Description

Recombinant Biotinylated Human FGFR4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu22-Asp369.

Product Background

Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

FGFR4

Synonyms

CD334; FGF R4; FGFR4; FGFR-4; MGC20292; JTK2; TKF

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Leu22-Asp369

Molecular Weight

The protein has a predicted MW of 41.4 kDa. Due to glycosylation, the protein migrates to 55-72 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human FGFR4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human FGFR4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human FGFR4 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human FGFR4 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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