Biotinylated Human FGFR4 Protein (FGF-HM4R4B)
Biotinylated Human FGFR4 Protein (FGF-HM4R4B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Leu22-Asp369
Catalog #FGF-HM4R4B
Regular price $525.00
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Product Description

Recombinant Biotinylated Human FGFR4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Leu22-Asp369.

Product Background

Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

Product Category

Recombinant Protein / Antibody discovery

Protein

FGFR4

Synonyms

CD334; FGF R4; FGFR4; FGFR-4; MGC20292; JTK2; TKF

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Leu22-Asp369

Molecular Weight

The protein has a predicted MW of 41.4 kDa. Due to glycosylation, the protein migrates to 55-72 kDa based on Bis-Tris PAGE result.

Product Tag

C-His-Avi

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biotinylated Human FGFR4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human FGFR4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human FGFR4 is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human FGFR4 is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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