- Express System: HEK293
- Product Tag: N-hFc (IgG1)-Avi
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Activity: Immobilized Anti-Galectin 1 Antibody, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Galectin 1, hFc-Avi Tag with the EC50 of 25.2ng/ml determined by ELISA.
- Amino Acid Range: Ala2-Asp135
Biotinylated Human Galectin 1 Protein (GAL-HM501B) Summary
Product Description |
Recombinant Biotinylated Human Galectin 1 Protein is expressed from HEK293 with hFc (IgG1) tag and Avi tag at the N-terminus.It contains Ala2-Asp135. |
Product Background |
Galectin 1(Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape. |
Biotinylated Human Galectin 1 Protein (GAL-HM501B) Specifications/Details
Protein |
GAL1 |
Synonyms |
Galectin-1; HLBP14; S-Lac lectin 1; LGALS1; GAL1; GBP; DKFZp686E23103; Galectin 1 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Ala2-Asp135 |
Molecular Weight |
The protein has a predicted MW of 43.11 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Anti-Galectin 1 Antibody, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human Galectin 1, hFc-Avi Tag with the EC50 of 25.2ng/ml determined by ELISA. |
Product Tag |
N-hFc (IgG1)-Avi |
Fluorophore |
Biotin-labeled |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
Other Available Proteins: