Biotinylated Human GIPR Nanodisc (GIP-HM14RNB)
Biotinylated Human GIPR Nanodisc (GIP-HM14RNB)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Met1-Cys466
Catalog #GIP-HM14RNB
Regular price $2,165.90
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Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Summary

Product Description

Recombinant Biotinylated Human GIPR Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Cys466.

Product Background

The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Specifications/Details

Protein
GIPR
Synonyms
GIP-R; GIPR; PGQTL2
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Met1-Cys466
Molecular Weight
The protein has a predicted MW of 63.8 kDa.
Activity
Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
Product Tag
C-His
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 200mM L-Arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human GIPR Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 18.70 nM as determined in SPR assay (Biacore T200). Biotinylated Human GIPR Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test).
Loaded Biotinylated Human GIPR Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 19.60 nM as determined in BLI assay (Gator® Prime). Loaded Biotinylated Human GIPR Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 19.60 nM as determined in BLI assay (Gator® Prime).
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