- Express System: HEK293
- Product Tag: C-His
- Activity: Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
- Amino Acid Range: Met1-Cys466
Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Summary
Product Description |
Recombinant Biotinylated Human GIPR Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Cys466. |
Product Background |
The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Specifications/Details
Protein |
GIPR |
Synonyms |
GIP-R; GIPR; PGQTL2 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Cys466 |
Molecular Weight |
The protein has a predicted MW of 63.8 kDa. |
Activity |
Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200). |
Product Tag |
C-His |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-Arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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