Name: Biotinylated Human GIPR Nanodisc (GIP-HM14RNB)
Brand: KactusBio
SKU: GIP-HM14RNB-100UG
Price: 2165.9 USD
Availability: InStock

Biotinylated Human GIPR Nanodisc (GIP-HM14RNB)

Biotinylated Human GIPR Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).

Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test).

Loaded Biotinylated Human GIPR Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 19.60 nM as determined in BLI assay (Gator® Prime).

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
Recomended Products: Biotinylated Nanodisc Control (CON-HM1NB)
Amino Acid Range: Met1-Cys466

Catalog #GIP-HM14RNB

Size

100UG

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Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Summary

Product Description	Recombinant Biotinylated Human GIPR Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Cys466.
Product Background	The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human GIPR Nanodisc (GIP-HM14RNB) Specifications/Details

Protein	GIPR
Synonyms	GIP-R; GIPR; PGQTL2
Accession	P48546-1
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Cys466
Molecular Weight	The protein has a predicted MW of 63.8 kDa.
Activity	Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test). The affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human GIPR Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 18.70 nM as determined in SPR assay (Biacore T200).
	Immobilized Biotinylated Human GIPR Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GIPR Antibody, hFc Tag with the EC50 of 25.5ng/ml determined by ELISA (QC Test).
	Loaded Biotinylated Human GIPR Nanodisc, His Tag on Streptavidin-Biosensor can bind Anti-GIPR Antibody, hFc Tag with an affinity constant of 19.60 nM as determined in BLI assay (Gator® Prime).