Name: Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B)
Brand: KactusBio
SKU: GTR-HM401B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B)

Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA.

Biotinylated Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human GITR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln26-Glu161

Catalog #GTR-HM401B

Size

100UG

500UG

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Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B) Summary

Product Description	Recombinant Biotinylated Human GITR/TNFRSF18 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln26-Glu161.
Product Background	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B) Specifications/Details

Protein	GITR/TNFRSF18
Synonyms	CD357; GITR; GITR-D; TNFRSF18; AITR
Accession	Q9Y5U5-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln26-Glu161
Molecular Weight	The protein has a predicted MW of 17.2 kDa. Due to glycosylation, the protein migrates to 26-28 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA.
	Biotinylated Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human GITR is greater than 95% as determined by SEC-HPLC.