Name: Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B)
Brand: KactusBio
SKU: GTR-HM401B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human GITR/TNFRSF18 Protein (GTR-HM401B)

Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA.

Biotinylated Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human GITR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln26-Glu161

Catalog #GTR-HM401B

Size

100UG

500UG

Order now, ships by:

[{"id":42618361282782,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"GTR-HM401B-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human GITR\/TNFRSF18 Protein (GTR-HM401B) - 100UG","public_title":"100UG","options":["100UG"],"price":52500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584184058078,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"GTR-HM401B-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human GITR\/TNFRSF18 Protein (GTR-HM401B) - 500UG","public_title":"500UG","options":["500UG"],"price":175000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Biotinylated Human GITR/TNFRSF18 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln26-Glu161.
Product Background	GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	GITR/TNFRSF18
Synonyms	CD357; GITR; GITR-D; TNFRSF18; AITR
Accession	Q9Y5U5-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln26-Glu161
Molecular Weight	The protein has a predicted MW of 17.2 kDa. Due to glycosylation, the protein migrates to 26-28 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GITR Ligand Trimer, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GITR, His Tag with the EC50 of 77.9ng/ml determined by ELISA.
	Biotinylated Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human GITR is greater than 95% as determined by SEC-HPLC.