Biotinylated Human GLP-1R Nanodisc (GLP-HM10NB) Summary
Product Description |
Recombinant Biotinylated Human GLP-1R Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ser463. |
Product Background |
Glucagon-like peptide-1 receptor (GLP-1R) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). GLP-1R emerged as an important pharmacological target for addressing T2DM, as it actively contributes to maintaining glucose homeostasis while promoting both β cell proliferation and insulin release. The impact of GLP-1R agonists such as semaglutide extends beyond diabetes control: they play a multifaceted role in regulating blood glucose levels by reducing hunger, moderating food intake, and managing body weight. Notably, GLP-1R agonists inhibit cancer progression in some malignant tumors. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Biotinylated Human GLP-1R Nanodisc (GLP-HM10NB) Specifications/Details
Protein |
GLP-1R |
Synonyms |
GLP-1 receptor; GLP-1-R; GLP-1R; GLP1R |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Met1-Ser463 |
Molecular Weight |
The protein has a predicted MW of 66.00 kDa. |
Activity |
Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 41.2ng/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 41.2ng/ml determined by ELISA. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed
