Biotinylated Human GLP-1R Protein-Nanodisc (GLP-HM10NB)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 53.1ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Ser463
Catalog #GLP-HM10NB
Regular price $1,875.00
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Product Description

Recombinant Biotinylated Human GLP-1R Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ser463.

Product Background

Glucagon-like peptide-1 receptor (GLP-1R) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). GLP-1R emerged as an important pharmacological target for addressing T2DM, as it actively contributes to maintaining glucose homeostasis while promoting both β cell proliferation and insulin release. The impact of GLP-1R agonists such as semaglutide extends beyond diabetes control: they play a multifaceted role in regulating blood glucose levels by reducing hunger, moderating food intake, and managing body weight. Notably, GLP-1R agonists inhibit cancer progression in some malignant tumors.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein

GLP-1R

Synonyms

GLP-1 receptor; GLP-1-R; GLP-1R; GLP1R

Accession

Species

Human

Biotinylated

yes

Amino Acid Range

Met1-Ser463

Molecular Weight

The protein has a predicted MW of 66.00 kDa.

Activity

Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 53.1ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His

Expression System

HEK293

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization and flow cytometry in mammalian cells.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 53.1ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human GLP-1R Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-GLP-1R Antibody, hFc Tag with the EC50 of 53.1ng/ml determined by ELISA (QC Test).

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support@kactusbio.us

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