Biotinylated Human GPRC5D Protein-Nanodisc (GPR-HM15NB)

Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 0.7ng/ml determined by ELISA (QC Test).

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 0.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Met1-Val345

Catalog #GPR-HM15NB

Size

100UG

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Product Description	Recombinant Biotinylated Human GPRC5D Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val345.
Product Background	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	GPRC5D
Synonyms	GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Accession	Q9NZD1-1
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Val345
Molecular Weight	The protein has a predicted MW of 51.70 kDa.
Activity	Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 0.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization and flow cytometry in mammalian cells.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 0.7ng/ml determined by ELISA (QC Test).