Biotinylated Human GPRC5D Nanodisc (GPR-HM15NB)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Val345
Catalog #GPR-HM15NB
Regular price $2,165.90
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Biotinylated Human GPRC5D Nanodisc (GPR-HM15NB) Summary

Product Description

Recombinant Biotinylated Human GPRC5D Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val345.

Product Background

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human GPRC5D Nanodisc (GPR-HM15NB) Specifications/Details

Protein
GPRC5D
Synonyms
GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Met1-Val345
Molecular Weight
The protein has a predicted MW of 51.70 kDa.
Activity
Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human GPRC5D Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate(5ug/ml). Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.6ng/ml determined by ELISA (QC Test).
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