Name: Biotinylated Human/Cynomolgus Her4/ErbB4 Protein (HER-HM4B4B)
Brand: KactusBio
SKU: HER-HM4B4B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human/Cynomolgus Her4/ErbB4 Protein (HER-HM4B4B)

Immobilized Biotinylated Human/Cynomolgus Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.

Biotinylated Human/Cynomolgus Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Biotinylated Human/Cynomolgus Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln26-Pro651

Catalog #HER-HM4B4B

Size

100UG

500UG

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Biotinylated Human/Cynomolgus Her4/ErbB4 Protein (HER-HM4B4B) Summary

Product Description	Recombinant Biotinylated Human/Cynomolgus Her4/ErbB4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln26-Pro651.
Product Background	Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Biotinylated Human/Cynomolgus Her4/ErbB4 Protein (HER-HM4B4B) Specifications/Details

Protein	Her4/ErbB4
Synonyms	p180erbB4; 4ICD; E4ICD; HER4; ErbB4; MGC138404; ALS19
Accession	Q15303-1(Human) / A0A2K5W0D7(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	yes
Amino Acid Range	Gln26-Pro651
Molecular Weight	The protein has a predicted MW of 72.7 kDa. Due to glycosylation, the protein migrates to 75-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human/Cynomolgus Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human/Cynomolgus Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.
	Biotinylated Human/Cynomolgus Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.