Name: Biotinylated Human Her4/ErbB4 Protein (HER-HM4B4B)
Brand: KactusBio
SKU: HER-HM4B4B-100UG
Price: 525.0 USD
Availability: InStock

Biotinylated Human Her4/ErbB4 Protein (HER-HM4B4B)

Immobilized Biotinylated Human Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.

Biotinylated Human Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human Her4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln26-Pro651

Catalog #HER-HM4B4B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Her4/ErbB4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln26-Pro651.
Product Background	Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	Her4/ErbB4
Synonyms	p180erbB4; 4ICD; E4ICD; HER4; ErbB4; MGC138404; ALS19
Accession	Q15303-1
Species	Human
Biotinylated	yes
Amino Acid Range	Gln26-Pro651
Molecular Weight	The protein has a predicted MW of 72.7 kDa. Due to glycosylation, the protein migrates to 75-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human Her4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.
	Biotinylated Human Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human Her4 is greater than 95% as determined by SEC-HPLC.