Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein (MHC-HE007B)

  • Express System: E.coli
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Biotinylated: yes
  • Exact Sequence: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide

Catalog: MHC-HE007B

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Product Description Recombinant Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide.

Product Background

Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

Product Category

Recombinant Protein

Target

HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer
Accession
MHC Form Monomer
Allele HLA-A*02:01

Species

Human

Exact Sequence

Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLVVVGAVGV peptide
Molecular Weight The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Tris-Bis PAGE result.

Product Tag

C-His-Avi

Express System

E.coli
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer is greater than 95% as determined by SEC-HPLC.
Biotinylated Human HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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