Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein

Express System: E.coli
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide

Catalog #MHC-HE009B

Price

$619³⁰

Size

Order by 4pm ET for delivery on:

Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein (MHC-HE009B) Summary

Product Description

Recombinant Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide.

Product Background

Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identified Rab protein that may downregulate TLR4 and TLR9-mediated inflammatory responses. Rab7b, believed to have similar function as Rab7, controls however vesicular trafficking from endosomes to the TGN. It is localized to late endosomes/lysosomes as well as the TGN. Rab7b interferes with enzymes delivery to lysosomes and with the retrograde Shiga toxin transport to the Golgi.

HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Specifications

Protein	HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV)
Synonyms	MHC; RAB7B
MHC Form	Monomer
Allele	HLA-A*02:01
Accession	A0A140T913(HLA-A*02:01)&P61769(B2M)&KLIIVGAIGV
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide
Molecular Weight	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Product Tag	C-His-Avi
Fluorophore	Biotin-labeled
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCI, 10% glycerol (pH 8.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer is greater than 95% as determined by SEC-HPLC.