Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein

Express System: E.coli
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer, His Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for HLA-A*11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 32.6ng/ml determined by ELISA.
Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGLAK peptide

Catalog #MHC-HE451B

Price

$341.00

/

Size

Order by 4pm ET for delivery on:

Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein (MHC-HE451B) Summary

Product Description	Recombinant Biotinylated Human HLA-A11:01&B2M&EGFR WT (KITDFGLAK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A11:01), Ile21-Met119(B2M) and KITDFGLAK peptide.
Product Background	The human telomerase catalytic subunit human telomerase reverse transcriptase (hTERT) is expressed in many human cancer cells derived from multiple tissues, but infrequently in normal cells. Thus, hTERT is an attractive candidate target for tumor immunotherapy. hTERT:540–548 peptide (p540, ILAKFLHWL) has been identified as an effective HLA-A*0201-restricted T-cell epitope, an effective T-cell-based cancer treatment, including vaccines, against hTERT will likely require the identification of other MHC class I-restricted epitopes in this antigen.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

Protein	HLA-A*02:01&B2M&TERT (ILAKFLHWL)
Synonyms	TERT; ILAKFLHWL
Accession	AAV53343.1(HLA-A*11:01)&P61769(B2M)&KITDFGLAK
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and KITDFGLAK peptide
Molecular Weight	The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human HLA-A11:01&B2M&EGFR WT (KITDFGLAK) Monomer, His Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for HLA-A11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 32.6ng/ml determined by ELISA.
Product Tag	C-His-Avi
Fluorophore	Biotin-labeled
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human HLA-A11:01&B2M&EGFR WT (KITDFGLAK) Monomer, His Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for HLA-A11:01&B2M&EGFR TCR, hFc Tag with the EC50 of 32.6ng/ml determined by ELISA.
	Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-A*11:01&B2M&EGFR WT (KITDFGLAK) Monomer is greater than 95% as determined by SEC-HPLC.

Other Available Proteins:

Finding available proteins...

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Loading...