Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein

Express System: E.coli
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer, His-Avi Tag at 1 ug/ml (100 ul/Well) on streptavidin(5 ug/ml) precoated plate. Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 28.6 ng/ml determined by ELISA (QC Test).
Amino Acid Range: Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide

Catalog #MHC-HE002B

Price

$619³⁰

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Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein (MHC-HE002B) Summary

Product Description	Recombinant Biotinylated Human HLA-A11:01&B2M&KRAS WT (VVGAGGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.

Protein	HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK)
Synonyms	MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD
MHC Form	Monomer
Allele	HLA-A*11:01
Accession	AAV53343.1 (HLA-A*11:01)&P61769 (B2M)&VVGAGGVGK
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVGAGGVGK peptide
Molecular Weight	The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer, His-Avi Tag at 1 ug/ml (100 ul/Well) on streptavidin(5 ug/ml) precoated plate. Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 28.6 ng/ml determined by ELISA (QC Test).
Product Tag	C-His-Avi
Fluorophore	Biotin-labeled
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20 mM Tris, 200 mM NaCl (pH 8.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer, His-Avi Tag at 1 ug/ml (100 ul/Well) on streptavidin(5 ug/ml) precoated plate. Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 28.6 ng/ml determined by ELISA (QC Test).
	Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-A*11:01&B2M&KRAS WT (VVGAGGVGK) Monomer is greater than 95% as determined by SEC-HPLC.