Name: Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein (MHC-HM462B)
Brand: KactusBio
SKU: MHC-HM462B-100UG
Price: 341.0 USD
Availability: InStock

Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein (MHC-HM462B)

Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and AVVGASGVGK peptide

Catalog #MHC-HM462B

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein (MHC-HM462B) Summary

Product Description	Recombinant Biotinylated Human HLA-A11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A11:01), Ile21-Met119 (B2M) and AVVGASGVGK peptide.
Product Background	RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has long been a vital research target for cancer. Its function is to transform the extracellular environment into a cascade of intracellular signal transduction. RAS mutant protein regulates tumor cell proliferation, apoptosis, metabolism and angiogenesis through downstream MAPK, PI3K and other signaling pathways.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Specifications

Protein	HLA-A*11:01&B2M&RASL11B (AVVGASGVGK)
Synonyms	RAS11B; AVVGASGVGK; MHC
MHC Form	Monomer
Accession	AAV53343.1(HLA-A*11:01)&P61769(B2M)&AVVGASGVGK
Species	Human
Biotinylated	yes
Amino Acid Range	Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and AVVGASGVGK peptide
Molecular Weight	The protein has a predicted MW of 50.25 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer is greater than 95% as determined by SEC-HPLC.