Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer Protein (MHC-HE004B)
Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer Protein (MHC-HE004B)
  • Express System: E.coli
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVGAIGVGK peptide
Catalog #MHC-HE004B
Regular price $619.30
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Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer Protein (MHC-HE004B) Summary

Product Description

Recombinant Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVGAIGVGK peptide.

Product Background

RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has long been a vital research target for cancer. Its function is to transform the extracellular environment into a cascade of intracellular signal transduction. RAS mutant protein regulates tumor cell proliferation, apoptosis, metabolism and angiogenesis through downstream MAPK, PI3K and other signaling pathways.

Product Category

Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Specifications

Protein
HLA-A*11:01&B2M&RAB7B (IVGAIGVGK)
Synonyms
RAS7B; IVGAIGVGK;

MHC Form

Monomer

Allele

HLA-A*11:01
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVGAIGVGK peptide
Molecular Weight
The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Product Tag
C-His-Avi
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer is greater than 95% as determined by SEC-HPLC. The purity of Biotinylated Human HLA-A*11:01&B2M&RAB7B (IVGAIGVGK) Monomer is greater than 95% as determined by SEC-HPLC.
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