Product Description |
Recombinant Biotinylated Human HLA-A*31:01&B2M&EGFR L858R (HVKITDFGR) Monomer Protein is expressed from HEK293 with His tag and Avi Tag at the C-terminus.It contains Gly25-Thr305(HLA-A*31:01), Ile21-Met119(B2M) and HVKITDFGR peptide. |
Product Background |
The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR, HER2/neu, Her 3 and Her 4. Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. |
Product Category |
Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs |
Protein |
HLA-A*31:01&B2M&EGFR L858R (HVKITDFGR) |
Synonyms |
ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2 |
MHC Form |
Monomer |
Allele |
HLA-A*31:01 |
Accession |
SOQ70041.1(HLA-A*31:01)&P61769(B2M)&HVKITDFGR |
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Gly25-Thr305(HLA-A*31:01), Ile21-Met119(B2M) and HVKITDFGR peptide |
Molecular Weight |
The protein has a predicted MW of 50.8 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed